Unemployment Rate in Sanilac County, MI was 6.00% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Sanilac County, MI reached a record high of 30.30 in April of 2020 and a record low of 3.30 in November of 2019. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Sanilac County, MI - last updated from the United States Federal Reserve on April of 2026.