Unemployment Rate in Santa Cruz County, CA was 6.40% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Santa Cruz County, CA reached a record high of 17.70 in April of 2020 and a record low of 3.40 in September of 2019. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Santa Cruz County, CA - last updated from the United States Federal Reserve on April of 2026.