Resident Population in Missouri was 6270.54100 Thous. of Persons in January of 2025, according to the United States Federal Reserve. Historically, Resident Population in Missouri reached a record high of 6270.54100 in January of 2025 and a record low of 3108.00000 in January of 1900. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Missouri - last updated from the United States Federal Reserve on March of 2026.