Unemployment Rate in Monroe County, MS was 3.90% in April of 2026, according to the United States Federal Reserve. Historically, Unemployment Rate in Monroe County, MS reached a record high of 23.70 in April of 2020 and a record low of 2.50 in April of 2024. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Monroe County, MS - last updated from the United States Federal Reserve on June of 2026.