Unemployment Rate in Knox County, KY was 6.30% in May of 2026, according to the United States Federal Reserve. Historically, Unemployment Rate in Knox County, KY reached a record high of 17.80 in April of 2020 and a record low of 4.30 in April of 2023. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Knox County, KY - last updated from the United States Federal Reserve on July of 2026.