Unemployment Rate in Knox County, KY was 5.70% in March of 2026, according to the United States Federal Reserve. Historically, Unemployment Rate in Knox County, KY reached a record high of 17.80 in April of 2020 and a record low of 4.40 in December of 2021. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Knox County, KY - last updated from the United States Federal Reserve on June of 2026.