Resident Population in San Mateo County, CA was 742.89300 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in San Mateo County, CA reached a record high of 768.65800 in January of 2017 and a record low of 556.30000 in January of 1971. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in San Mateo County, CA - last updated from the United States Federal Reserve on April of 2026.