Resident Population in Lafayette County, MO was 33.51100 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Lafayette County, MO reached a record high of 33.51100 in January of 2024 and a record low of 26.62600 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Lafayette County, MO - last updated from the United States Federal Reserve on April of 2026.