Resident Population in Guthrie County, IA was 10.77400 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Guthrie County, IA reached a record high of 12.70000 in January of 1972 and a record low of 10.59800 in January of 2021. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Guthrie County, IA - last updated from the United States Federal Reserve on April of 2026.