Unemployment Rate in St. Joseph County, MI was 4.20% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in St. Joseph County, MI reached a record high of 27.90 in April of 2020 and a record low of 2.30 in August of 1999. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in St. Joseph County, MI - last updated from the United States Federal Reserve on April of 2026.