Resident Population in Greenville, NC (MSA) was 180.78300 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Greenville, NC (MSA) reached a record high of 181.25700 in January of 2019 and a record low of 153.15600 in January of 2000. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Greenville, NC (MSA) - last updated from the United States Federal Reserve on April of 2026.