Resident Population in St. Mary's County, MD was 116.46900 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in St. Mary's County, MD reached a record high of 116.46900 in January of 2024 and a record low of 47.38800 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in St. Mary's County, MD - last updated from the United States Federal Reserve on April of 2026.