Eugene-Springfield, OR - Resident Population in Eugene, OR (MSA) was 382.39600 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Eugene-Springfield, OR - Resident Population in Eugene, OR (MSA) reached a record high of 386.18700 in January of 2022 and a record low of 323.50500 in January of 2000. Trading Economics provides the current actual value, an historical data chart and related indicators for Eugene-Springfield, OR - Resident Population in Eugene, OR (MSA) - last updated from the United States Federal Reserve on September of 2025.