Resident Population in Cotton County, OK was 5.50300 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Cotton County, OK reached a record high of 7.33800 in January of 1980 and a record low of 5.44400 in January of 2021. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Cotton County, OK - last updated from the United States Federal Reserve on April of 2026.