Unemployment Rate in Carlisle County, KY was 3.70% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Carlisle County, KY reached a record high of 13.10 in April of 1991 and a record low of 2.70 in November of 1997. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Carlisle County, KY - last updated from the United States Federal Reserve on April of 2026.