Resident Population in Owensboro, KY (MSA) was 113.58300 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Owensboro, KY (MSA) reached a record high of 119.43300 in January of 2019 and a record low of 95.62800 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Owensboro, KY (MSA) - last updated from the United States Federal Reserve on April of 2026.