Resident Population in Otsego County, MI was 26.08300 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Otsego County, MI reached a record high of 26.08300 in January of 2024 and a record low of 10.42200 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Otsego County, MI - last updated from the United States Federal Reserve on April of 2026.