Resident Population in Cherokee County, AL was 26.13800 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Cherokee County, AL reached a record high of 26.25400 in January of 2019 and a record low of 15.60600 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Cherokee County, AL - last updated from the United States Federal Reserve on April of 2026.