Unemployment Rate in Tuscola County, MI was 5.70% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Tuscola County, MI reached a record high of 27.60 in April of 2020 and a record low of 3.30 in October of 1997. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Tuscola County, MI - last updated from the United States Federal Reserve on April of 2026.