Unemployment Rate in Sioux City, IA-NE-SD (MSA) was 3.50% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Sioux City, IA-NE-SD (MSA) reached a record high of 10.00 in April of 2020 and a record low of 1.90 in October of 1999. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Sioux City, IA-NE-SD (MSA) - last updated from the United States Federal Reserve on April of 2026.