Unemployment Rate in Seneca County, OH was 4.50% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Seneca County, OH reached a record high of 18.80 in April of 2020 and a record low of 3.10 in April of 2023. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Seneca County, OH - last updated from the United States Federal Reserve on April of 2026.