Unemployment Rate in Anderson County, SC was 4.60% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Anderson County, SC reached a record high of 13.40 in January of 2010 and a record low of 1.70 in September of 2019. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Anderson County, SC - last updated from the United States Federal Reserve on April of 2026.