Total Gross Domestic Product for Roanoke, VA (MSA) was 21742.56400 Mil. of $ in January of 2023, according to the United States Federal Reserve. Historically, Total Gross Domestic Product for Roanoke, VA (MSA) reached a record high of 21742.56400 in January of 2023 and a record low of 10602.28300 in January of 2001. Trading Economics provides the current actual value, an historical data chart and related indicators for Total Gross Domestic Product for Roanoke, VA (MSA) - last updated from the United States Federal Reserve on April of 2026.