Resident Population in Springfield, MO (MSA) was 500.69400 Thous. of Persons in January of 2025, according to the United States Federal Reserve. Historically, Resident Population in Springfield, MO (MSA) reached a record high of 500.69400 in January of 2025 and a record low of 209.08400 in January of 1970. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Springfield, MO (MSA) - last updated from the United States Federal Reserve on May of 2026.