Unemployment Rate in Oxford County, ME was 3.60% in December of 2025, according to the United States Federal Reserve. Historically, Unemployment Rate in Oxford County, ME reached a record high of 12.20 in February of 2010 and a record low of 2.40 in August of 2022. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in Oxford County, ME - last updated from the United States Federal Reserve on April of 2026.