Resident Population in Syracuse, NY (MSA) was 655.18900 Thous. of Persons in January of 2024, according to the United States Federal Reserve. Historically, Resident Population in Syracuse, NY (MSA) reached a record high of 663.13200 in January of 2010 and a record low of 644.43700 in January of 2007. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Syracuse, NY (MSA) - last updated from the United States Federal Reserve on April of 2026.